Monga anthu, kuchepa kwa ntchito ya ubongo kumaonekera bwino. Mwa anthu okalamba 20-49, ambiri anayamba kuzindikira kuchepa kwa zinthu mwanzeru akamakumbukira kukumbukira kapena kuiwala. Kwa okalamba 50-59, kuzindikira kuchepa kwa kuzindikira nthawi zambiri kumabwera pamene ayamba kumva kumbukira.
Mukayang'ana njira zowonjezera ubongo, magulu osiyana azaka zosiyanasiyana amayang'ana mbali zosiyanasiyana. Anthu azaka za zaka 20-29 amakonda kuyang'ana kwambiri kukonza kugona kuti azitha kupititsa patsogolo magwiridwe antchito (44.7%), pomwe anthu ali ndi chidwi chofuna kuchepetsa kutopa (47.5%). Kwa azaka zokhala ndi zaka 40-59, chidwi chimawerengedwa kuti chikonzero cha ntchito ya ubongo (zaka 40-49: 44%, zaka 50-59: 43.4%).
Zosakaniza zodziwika bwino ku Japan Msika Waumoyo wa Japan
Mogwirizana ndi zochita za padziko lonse lapansi zofunafuna moyo wathanzi, msika wa chakudya cha Japan makamaka umatsindika njira zothetsera mavuto azaumoyo, ndi thanzi la ubongo kukhala mfundo yofunika kwambiri. Pofika pa Disembala 11, 2024, Japan anali atalembetsa zakudya 1,012 Mwa awa, Gaba anali pophatikiza nthawi zambiri, kenakolutuin/Zeaxanjanthin, tsamba la ginkgo chimatulutsa (Flavonoids, Terpenoids),Dha, Bifidobacterium McC1274, Porbaca Oleracea saponins, paclitaxel, Italizolidine Peptides,Pqq, ndipo Errgengoine.
1. GABA
GABA (γ-aminobutyric acid) ndi pro pro proteininoge acid yoyamba kupezeka ndi oyang'anira ndi ogwira ntchito mu mbatata tuber minyewa mu 1949. Mu 1950, Roberter et al. Adazindikiritsa Gaba mu ubongo wa Mammalian, wopangidwa kudzera mu α-dekarboxuslation ya glutamate kapena mchere wake, wopachitsidwa ndi glutamate decarboxlase.
GabA ndi neurotransmitter yovuta kwambiri yomwe imapezeka kwambiri mu dongosolo lamanjenje lamanjenje lamanjenje. Ntchito yake yayikulu ndikuchepetsa chidwi cha neuronol poletsa kufalikira kwa zizindikiro za neural Nearal. Mu ubongo, moyenera pakati pa zoletsa zamitsempha yolumikizidwa ndi Gaba ndi zowoneka bwino zolumikizidwa ndi glubamate ndizofunikira kuti musunge cell nembanemba.
Kafukufuku akuwonetsa kuti Gaba amatha kuletsa kusintha kwa ma neuroodegenative ndikuwongolera kukumbukira komanso kugwira ntchito kwanzeru. Kafukufuku wa nyama akusonyeza kuti Gaba adasintha kukumbukira kwa nthawi yayitali ku mbewa ndi kutsika kwanzeru ndipo amalimbikitsa kuchuluka kwa neuroendocration PC-12 maselo. M'mayesero azachipatala, Gaba awonetsedwa kuti awonjezere matenda a neurotrophic yaubongo (BDNF) ndikuchepetsa matenda a Dementia ndi Alzheimer's Alzheimer Akazi Akuluakulu.
Kuphatikiza apo, Gaba ali ndi zotsatirapo zabwino za mikhalidwe, kupsinjika, kutopa, ndi kugona. Kafukufuku akuwonetsa kuti gaba ndi L-Theanine imatha kuchepetsa kugona tulo, ndikuwonjezera nthawi yayitali, ndikuphatikiza mawu a Gaba ndi Glutamate Glunur1 rewala.
2. Lutuin / Zeaxansthin
LutuinNdi mpweya wa oxygenoid wopangidwa ndi zotsalira 8 isoprene, ma polyene omwe ali ndi ma polyge omwe ali ndi maulalo asanu ndi anayi, omwe amatenga ndikuwunika ndikuwunika mosiyanasiyana, ndikupereka utoto wapadera.Zeaxanjanthinndi isomer wa lutein, wosiyana pamalopo olumikizana awiri mu mphete.
Lutein ndi Zeaxansthinndi utoto waukulu mu retina. Lutein amapezeka kwambiri ku Petaral retina, pomwe Zeaxanjanthin amakhazikika ku Macumula Vula. Zotsatira zalutein ndi ZeaxansthinChifukwa maso amaphatikizapo kukonza masomphenyawo, kupewa mbiri yokhudzana ndi zaka zokhudzana ndi zaka zambiri (AMD), ojambula, glaucoma, ndikuletsa retinopathy m'makamwa osakhalitsa.
Mu 2017, ofufuza ochokera ku Yunivesite ya Georgia anapeza kutilutein ndi ZeaxansthinSinthani bwino thanzi laubongo mwa akulu akulu. Kafukufukuyu adawonetsa kuti otenga nawo gawo apamwamba alutein ndi ZeaxansthinChowonetsedwa ntchito yotsika ya Brain Brain Paubongo mukamakumbukira ntchito zamagetsi, kupereka umboni wapamwamba kwambiri.
Kuphatikiza apo, kafukufuku adanenanso kuti lutux 2020, chowonjezera cha Lutein, chowonjezera cha BDNF (ubongo wopangidwa ndi ma neuron, komanso kusiyanasiyana kwa ma neurons, kukumbukira, komanso ntchito yanzeru.
(Njira zopangira lutein ndi Zeaxanjanthin)
3..
Ginkgo biloba, nyama zomwe zikanatsala mu banja la Ginkgo, limatchedwa "moyo wamoyo." Masamba ndi mbewu zake zimagwiritsidwa ntchito mu kafukufuku wa pharmacologicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogicalogical ndipo ndi imodzi mwazinthu zachilengedwe zomwe zimagwiritsidwa ntchito padziko lonse lapansi. Mankhwala ogwirira ntchito ku Ginkgo amasamba makamaka ma flavonoids ndi a Terpenoids, omwe ali ndi katundu monga kuchepetsa, kusintha malingaliro, ndikuwateteza kuwonongeka kwa chiwindi cha chiwindi.
Chikondwerero cha World Health Organish cha Mankhwala Omera Zakudya ZosiyanasiyanagilaniZowonjezera za Leafs ziyenera kukhala ndi 22-27% flycosides glycosides ndi 5-7% terpenoids, ndi ginkgolic acid zomwe zili pansipa 5 mg / kg. Ku Japan, thanzi la chakudya ndi zakudya zomwe zimapangitsa kuti zitheke za Ginkgo Tizipeza zosachepera 6%, ndi ginkgolic acid osakwana 5 ppm. Abwino olimbikitsidwa tsiku lililonse achikulire ali pakati pa 60 ndi 240 mg.
Kafukufuku wasonyeza kuti kumwa kwa nthawi yayitali ginkgo, poyerekeza ndi placebo, kumatha kulimbikitsa kwambiri ntchito zina zowoneka bwino, kuphatikizapo kulondola kukumbukira komanso luso loweruza. Kuphatikiza apo, Ginkgo Tingafinye osokoneza bongo ndi ntchito.
4. DHA
Dha. Zimakhala zochuluka mu nsomba zam'nyanja ndi zopangidwa zawo, makamaka nsomba zamafuta, zomwe zimapereka 0,68-1.3 magalamu a DHA pa 100 magalamu. Zakudya zopangidwa ndi nyama monga mazira ndi nyama zimakhala ndi zochepa za DHA. Kuphatikiza apo, mkaka wamawere wa anthu ndi mkaka wina umakhalanso ndi DHA. Kafukufuku woposa azimayi opitilira 2,400 omwe amapezeka kuti muyezo wa DA m'mawere ndi 0.32% ya mafuta okwanira 0.32% mpaka 1.4%, ndi kuchuluka kwa mikositi yabwino kwambiri mkaka wa m'mawere.
DHA imalumikizidwa ndi chitukuko cha ubongo, ntchito, ndi matenda. Kafukufuku wowonjezera akuwonetsa kutiDhaimatha kukulitsa neurotranstation, kukula kwa neuronul, ma synaptic pulasitiki, ndi neurotransmitter. Kusanthula kwa Metal kwa mayesero 15 osasinthika kunawonetsa kuti masiku onse a Dha a 580 mg yamphamvu kwambiri.
Makina a DHA amagwiritsa ntchito: 1) Kubwezeretsa N-3 / N-6 Pufa; 2) Kuletsa minyewa yokhudzana ndi zaka zokhudzana ndi minyewa ya M1 M1 M1 M1 Microglivation yowonjezera; 3) Pogonjetsa Astrocyte Phenotype mwa kutsitsa A1 1 ndi S100B; 4) Kulepheretsa njira ya Probdnf / P75 Kuyika Panjira Popanda Kusintha kwa Ubongo - Kuchokera ku Neurotrophic Factor Factor - Kinase B Ndipo 5) Kulimbikitsa kupulumuka kwa neuronol mwa kuwonjezera kuchuluka kwa Phosphatridylserline, yomwe imathandizira mapuloteni kinase b (akt) membrane kutulutsa ndi kutsegula.
5. Bifidobacterium McC1274
Matumbo, nthawi zambiri amatchedwa "ubongo wachiwiri," wawonetsedwa kukhala ndi mgwirizano wofunikira ndi ubongo. Matumbo, ngati chiwalo chokhala ndi mayendedwe aukhondo, amatha kugwira ntchito modziyimira pawokha popanda malangizo aubongo. Komabe, kulumikizana pakati pa m'matumbo ndi ubongo kumasungidwa kudzera mu mantha a oyimira pawokha, zizindikiro za mahomoni, ndi ma cytokines, ndikupanga zomwe zimadziwika kuti "matumbo a ubongo."
Kafukufuku wawonetsa kuti mabakiteriya a m'matumbo amatenga gawo pakuwunikira mapuloteni a β-Amyloiiiiiiiid, cholembera chofunikira mu matenda a Alzheimer's. Poyerekeza ndi zowongolera zothetsa thanzi, odwala a Alzheimer achepetsa macrabitaation osiyanasiyana, ndi kuchepa kwa bifidobacterium.
Mu maphunziro okhudzana ndi anthu pa anthu omwe ali ndi vuto lofananira (MCI), kugwiritsa ntchito bifidobachium mcc1274 kwambiri. Zambiri m'madera oterowo pokumbukira nthawi yomweyo, kuthekera kowoneka, kukonza kowoneka bwino, komanso kukumbukira kuchedwa kunasinthidwanso kwambiri.
Post Nthawi: Jan-07-2025