Posachedwapa, Akay Bioactives, wopanga zinthu zopatsa thanzi ku US, adafalitsa kafukufuku wopangidwa mwachisawawa, woyendetsedwa ndi placebo pazotsatira za Immufen™ pophatikiza ndi mild allergic rhinitis, zovuta za turmeric ndi phwetekere woledzera waku South Africa. Zotsatira za kafukufukuyu zinasonyeza kuti turmeric ndi South Africa zowonjezera zowonjezera zimatha kuthetsa matupi awo sagwirizana ndi rhinitis.
Allergic Rhinitis, nkhawa zaumoyo kwa anthu opitilira 400 miliyoni
Allergic rhinitis (AR) ndi matenda otupa omwe amakhudza kwambiri anthu opitilira 400 miliyoni padziko lonse lapansi, ndipo kuchuluka kwake kwakula zaka zingapo zapitazi. Makhalidwe ake ndi monga kuyetsemula, kutulutsa mphuno, kupindika m’mphuno, ndi kuyabwa kwa maso, mphuno, ndi m’kamwa. Nthawi zambiri zimagwirizanitsidwa ndi matenda ena monga mphumu, conjunctivitis, ndi sinusitis, zomwe zingayambitse kutsika kwa moyo, kusokonezeka kwa chidziwitso, kusagwira ntchito bwino, komanso kugona bwino.
Njira zazikuluzikulu za pathogenesis ya allergenic rhinitis ndi kusalinganika pakati pa mtundu wa 1 wothandizira T maselo (Th1) ndi mtundu wa 2 wothandizira T maselo (Th2), ndi kusalinganika pakati pa chitetezo chachibadwa ndi chosinthika kuphatikizapo ma antigen-presenting cells, lymphocytes ndi T maselo.
Chithandizo cha matupi awo sagwirizana rhinitis nthawi zambiri chimachitidwa ndi antihistamines kapena decongestants ya m'mphuno, ndipo ngakhale kuti antihistamines asinthidwa kwa mibadwo ingapo, angayambitsebe mavuto osiyanasiyana monga mutu, kutopa, kugona, pharyngitis, ndi chizungulire. Thandizo lazitsamba tsopano likutuluka ngati mankhwala ochiritsira otetezeka kapena amtundu wina kuti athe kukonza ndi/kapena kusamalira mikhalidwe ya AR.
Tomato Woledzera wa Turmeric + South Africa Amathandizira Kwambiri AR
Mu kafukufuku wofalitsidwa ndi Akay Bioactives, otenga nawo mbali a 105 adapatsidwa mwayi wolandila turmeric ndi tomato woledzera waku South Africa (CQAB, kapisozi iliyonse ya CQAB imaphatikizapo 95 ± 5 mg curcumin ndi 125 mg ya phwetekere yaku South Africa yoledzera), bioavailable curcumin (CGM, kapisozi iliyonse ya CGM imakhala ndi 250 mg curcumin), kapena placebo kawiri tsiku lililonse masiku 28. Pofufuza za covariance (ANCOVA), CQAB inapezeka kuti imachepetsa kwambiri zizindikiro zokhudzana ndi rhinitis poyerekeza ndi CGM ndi placebo. Poyerekeza ndi placebo: kutsekeka kwa mphuno kunachepetsedwa ndi 34.64%, mphuno yothamanga ndi 33.01%, mphuno yoyabwa ndi 29.77%, kuyetsemula ndi 32.76%, ndi Total Nasal Symptom Score (TNSS) ndi 31.62%; poyerekeza ndi CGM: kutsekeka kwa mphuno kunachepetsedwa ndi 31.88%, mphuno yothamanga ndi 53.13%, mphuno yoyabwa ndi 24.98%, kuyetsemula ndi 2.93%, ndi 25.27% kutsika kwa Total Nasal Symptom Score (TNSS).
The Ayurvedic monograph Dhanwantari Nighantu amatchula turmeric ngati chitetezo ndi chithandizo cha rhinitis. Biringanya woledzera amagwiritsidwa ntchito pochiza kutsekeka kwa mphuno (kuletsa kutsokomola ndi kupuma movutikira) komanso kuwongolera mphamvu. Kuphatikiza kwa zitsamba ziwirizi kumatha kukhala ndi zotsatira za synergistic pharmacological ndipo potero kumapangitsa kuti matupi awo sagwirizana ndi rhinitis.Akay Bioactives adafalitsa kafukufuku yemwe adapeza kuti kuthekera kwa curcumin kuwongolera chitetezo chamthupi kumadalira kuyanjana kwake ndi ma modulators osiyanasiyana, monga B cell, T. maselo, maselo a dendritic, maselo akupha achilengedwe, ma neutrophils, ndi macrophages; ndi kuti zosakaniza zogwira ntchito za phwetekere kuledzera ku South Africa (kuledzera phwetekere lactone ndi The yogwira zigawo za South Africa hepatica (hepatica lactone ndi hepatica lactone glycosides) akhoza kukhala ndi zotsatira zawo immunomodulatory polimbikitsa ndi activating macrophages.
Anthu omwe ali ndi zizindikiro za matupi awo sagwirizana ndi rhinitis amakonda kugona kosagona bwino, zomwe zingayambitse kuchepa kwa luso la kuphunzira, kuchepa kwa kuphunzira / kuchita bwino, motero kutsika kwa moyo. Ngakhale kuti curcumin mu turmeric ikhoza kuchepetsa kuchedwa kwa tulo ndikuwonjezera nthawi yogona mu mbewa; kuledzera kwa lactone ku South Africa kuledzera kumatha kuthetsa nkhawa komanso kugona bwino. Choncho, zikhoza kuganiziridwa kuti zotsatira za synergistic za zakumwa zoledzeretsa za ku South Africa ndi curcumin zikhoza kubweretsa zotsatira zolimbikitsa kugona kwa CQAB.
Kuonjezera apo, omwe adachita nawo kafukufuku wofalitsidwa adanena kuti kuchuluka kwa matenda a maganizo, kutopa, ndi kuchepa kwa mphamvu kumayambiriro kwa phunzirolo. Ndipo curcumin idasintha kwambiri malingaliro oyipa. Mofananamo, South African Drunken Tomato Extract imadziwika kuti imachepetsa kupsinjika ndikuwonjezera mphamvu, potero kumapangitsa moyo kukhala wabwino komanso kuthekera kogwira ntchito. Mwa zina, Tomato Woledzera wa ku South Africa amatha kuchepetsa ntchito ya hypothalamic-pituitary-adrenal axis (HPA). Poyankha kukakamiza kovutitsa, axis ya HPA mosalunjika imathandizira kuchulukira kwa cortisol ndi dehydroepiandrosterone (DHEA), ndipo kuchepa kwa DHEA ndizomwe zimayambitsa mavuto ambiri am'maganizo, m'maganizo komanso m'maganizo.
Kugwiritsa Ntchito Kwa Tomato Woledzeretsa wa Turmeric + waku South Africa
Deta ya futuremarketinsights ikuwonetsa kuti kukula kwa msika wapadziko lonse lapansi kumatha kufika $ 4,419.3 miliyoni pofika 2023. Kukula pa CAGR ya 5.5% panthawi yolosera (2023-2033), msika wonse udzakhala wamtengo wapatali kuposa $ 7,579.2 miliyoni pofika 2033.
Pakadali pano, msika wapadziko lonse lapansi wazinthu zoledzeretsa ku South Africa ukhoza kufika $698.0 miliyoni mu 2023 ndipo ukuyembekezeka kufika $1,523.0 miliyoni pofika 2033. Ikukula pa CAGR ya 8.1% panthawi yolosera (2023-2033). Zotsatira za synergistic za turmeric ndi zoledzeretsa za ku South Africa zatsimikiziridwa kuti zili ndi thanzi labwino ndipo zimagwiritsidwa ntchito pazinthu zosiyanasiyana.
Thanzi Labwinoakhoza kusinthidwa mochuluka
(1) Chowonjezera chomwe chili ndi turmeric ndi hepatica yaku South Africa, yomwe imatha kuwonjezeredwa kumadzi otentha kapena mkaka ndikudyedwa palimodzi. Imawonjezera chitetezo chokwanira, mphamvu ndi kupirira, imalimbana ndi chimfine ndi chimfine, imathandizira chimbudzi ndi masomphenya.
(2) Chowonjezera chomwe chili ndi curcumin ndi tomato waku South Africa, mankhwalawa amatha kukhala odzaza ndi mphamvu, kuthandizira kukhazikika kwamalingaliro, ndikuwonetsetsa kuti mafupa ndi ziwalo zina za thupi zikuyenda bwino.
(3) Kuphatikizika kwa botanical komwe kumakhala ndi hepatica ya ku South Africa ndi curcumin, komwe kumachepetsa kupsinjika komwe kumabwera chifukwa cha kupsinjika komanso kukhala ndi chisangalalo.
(4) Zakumwa zokhala ndi turmeric ndi ndudu zoledzeretsa za ku South Africa, zomwe zilibe shuga wowonjezera, zimathandiza anthu kukulitsa malingaliro awo ndikusungabe malingaliro.
Nthawi yotumiza: Nov-21-2024