Zosakaniza Zosiyanasiyana | N / A |
Cas No | 71963-77-4 |
Chemical Formula | C16H26O5 |
Kulemera kwa maselo | 298.37 |
EINECS no. | 663-549-0 |
Malo osungunuka | 86-88 ° C |
Malo otentha | 359.79 ° C (kuyerekeza molakwika) |
Kuzungulira kwachindunji | D19.5+171°(c=2.59inCHCl3) |
Kuchulukana | 1.0733 (kuyerekeza movutikira) |
Index of refraction | 1.6200 (chiyerekezo) |
Zosungirako | Kutentha kwapanyumba |
Kusungunuka | DMSO≥20mg/mL |
Maonekedwe | Ufa |
Mawu ofanana ndi mawu | Artemetherum/Artemtherin/Dihydroartemisininmethylether |
Kusungunuka | Zosungunuka mu Madzi |
Magulu | Zomera Zomera, Zowonjezera, Zaumoyo |
Mapulogalamu | Anti-malungo |
Artemether ndi sesquiterpene lactone yomwe imapezeka mumizu yaArtemisia pachaka, omwe amadziwika kuti sweet chowawa. Ndi mankhwala amphamvu oletsa malungo omwe amagwiritsidwa ntchito pochiza ndi kupewa malungo. Artemisinin, kalambula bwalo wa artemether, idatulutsidwa koyamba kuchokera ku mbewuyi mu 1970s, ndipo kupezeka kwake kudapangitsa kuti wofufuza waku China, Tu Youyou, alandire Mphotho ya Nobel mu Medicine mu 2015.
Artemether amagwira ntchito powononga tizilombo toyambitsa malungo. Malungo amayamba ndi tizilombo toyambitsa matenda totchedwa Plasmodium, timene timapatsira anthu mwa kulumidwa ndi udzudzu waukazi wotchedwa Anopheles. Tizilombo toyambitsa matenda tikalowa m’thupi la munthu, timachulukirachulukira m’chiŵindi ndi m’maselo ofiira, ndipo zimenezi zimachititsa kutentha thupi, kuzizira, ndi zizindikiro zina zonga chimfine. Ngati sanalandire chithandizo, malungo akhoza kupha.
Artemether ndiwothandiza kwambiri polimbana ndi mitundu ina yosamva mankhwala ya Plasmodium falciparum, yomwe imachititsa kuti anthu ambiri azifa chifukwa cha malungo padziko lonse lapansi. Zimagwiranso ntchito polimbana ndi mitundu ina ya tizirombo ta Plasmodium toyambitsa malungo. Artemether nthawi zambiri amaperekedwa limodzi ndi mankhwala ena, monga lumefantrine, kuti achepetse chiopsezo cha kukana mankhwala.
Kupatula kugwiritsa ntchito ngati mankhwala oletsa malungo, artemether yapezekanso kuti ili ndi mankhwala ena. Kafukufuku wasonyeza kuti ali ndi anti-yotupa, anti-tumor, ndi anti-virus ntchito. Amagwiritsidwa ntchito pochiza nyamakazi, lupus, ndi matenda ena a autoimmune. Adafufuzidwanso kuti atha kuchiza COVID-19, ngakhale kafukufuku wochulukirapo akufunika kuti atsimikizire kugwira ntchito kwake.
Artemether nthawi zambiri imakhala yotetezeka komanso yololera bwino ikagwiritsidwa ntchito monga mwauzira. Komabe, monga mankhwala onse, angayambitse mavuto. Zotsatira zofala kwambiri za artemether ndi monga nseru, kusanza, chizungulire, ndi mutu. Nthawi zina, zimatha kuyambitsa zovuta zina, monga kugunda kwa mtima, khunyu, ndi kuwonongeka kwa chiwindi.
Pomaliza, artemether ndi mankhwala amphamvu oletsa malungo omwe asintha chithandizo cha malungo ndi kupewa. Kupezedwa kwake kwapulumutsa miyoyo yambiri ndipo kwachititsa kuti asayansi adziwike. Zina zake zochizira zimamupangitsa kukhala wodalirika wochizira matenda ena. Ngakhale zingayambitse mavuto, ubwino wake umaposa zoopsa zake zikagwiritsidwa ntchito moyang'aniridwa ndi achipatala.
Mafomu omwe amagwiritsidwa ntchito kwambiri ndi mapiritsi, makapisozi ndi jakisoni. Mitundu ya mankhwalawa ndi mankhwala oletsa malungo, ndipo chigawo chachikulu ndi artemether. The causative khalidwe la mapiritsi artemether anali woyera mapiritsi. Khalidwe la artemether capsule ndi capsule, zomwe zili mkati mwake ndi ufa woyera; Makhalidwe a mankhwala a jakisoni wa artemether ndi opanda utoto mpaka mafuta achikasu owala - ngati madzi.
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